Low-intensity magnetic fields assisted alignment of actin filaments

Kaur, Harsimran and Kumar, Suresh and Kaur, Inderpreet and Singh, Kashmir and Bharadwaj, L.M. (2010) Low-intensity magnetic fields assisted alignment of actin filaments. International Journal of Biological Macromolecules, 47 (3). pp. 371-374. ISSN 1879-0003

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Official URL: http://www.sciencedirect.com/science/article/pii/S...


This article represents the effects on actin filaments attached to magnetic nanoparticles when exposed to low-intensity magnetic field. In this approach, streptavidin functionalized magnetic nanoparticles were used to demonstrate the alignment of actin filament under external magnetic field of 22 mT. To check the directionality of myosin on magnetically aligned actin filaments in vitro motility assay was performed with myosin and average velocity was found to be 3.50 μm/s. It was observed that myosin moves in the direction in which actin filaments were magnetically aligned. This approach will explore the capability of integrating molecular motor into microelectronics mechanical system (MEMS) and nanoelectro-mechanical system (NEMS).

Item Type: Article
Uncontrolled Keywords: Actin; Myosin; Magnetic field; Alignment; In vitro motility
Subjects: CSIO > Nano Science and Nano Technology
Depositing User: Ms T Kaur
Date Deposited: 02 Feb 2012 14:38
Last Modified: 10 Apr 2012 15:08
URI: http://csioir.csio.res.in/id/eprint/151

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