Tuteja, S.K. and Sabherwal, Priyanka and Deep, Akash and Rastogi, Richa and Paul, A.K. and Suri, C.R. (2014) Biofunctionalized rebar graphene (f-RG) for label-free detection of cardiac marker troponin I. ACS Applied Materials and Interfaces, 6. pp. 14767-14771. ISSN 1944-8244
Full text not available from this repository.Abstract
One-step microwave-assisted unscrolling of carbon nanotubes to form functionalized rebar graphene (f-RG) is reported. The well-characterized f-RG on an interdigitated electrode biochip in a FET configuration showed enhanced electronic properties, as demonstrated with I-V characteristics. The developed device was biofunctionalized with specific anti-cTnI antibodies exhibiting a shift of threshold voltage from -2.15 V to -0.5 V and decrease in electron mobility from 3.609 × 10(4) to 8.877 × 10(3) cm(2) V(-1) s(-1). The new sensing strategy holds great promise for its applicability in diagnostics exhibiting high sensitivity (∼ 1 pg/mL) and specificity toward cardiac marker (cTnI).
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | biochip; carbon nanotubes; cardiac marker; clinical diagnostics; functionalized rebar graphene; troponin I |
| Subjects: | CSIO > Materials Science CSIO > Nano Science and Nano Technology |
| Divisions: | Nano Science and Nano Technology |
| Depositing User: | Ms. Jyotsana |
| Date Deposited: | 20 Jul 2015 10:48 |
| Last Modified: | 20 Jul 2015 10:48 |
| URI: | http://csioir.csio.res.in/id/eprint/490 |
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