Luminescent nanocrystal metal organic framework based biosensor for molecular recognition

Kumar, Pawan and Kumar, Parveen and Bharadwaj, L.M. and Paul, A.K. and Deep, Akash (2014) Luminescent nanocrystal metal organic framework based biosensor for molecular recognition. Inorganic Chemistry Communications, 43. pp. 114-117. ISSN 1387-7003

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Abstract

A nanocrystal metal organic framework (NMOF1) has been investigated for molecular recognition. NMOF1 {[Cd(atc)(H2O)2]n} has been synthesized by the reaction of Cd(II) ions with the sodium salt of ‘atc’ (‘atc’ = 2-aminoterephthalic acid) in aqueous medium at room temperature. Pendent single bondCOOH group of the organic linker was activated using EDC [(1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide] intermediated organic reaction, followed by the bioconjugation of NMOF1 with anti-BSA (anti-bovine serum albumin). NMOF1/anti-BSA complex has been used for the sensing of BSA (bovine serum albumin) based on the fluorescence quenching phenomena. Estimated limit of detection of the proposed molecular probe is 7 mg/mL.

Item Type: Article
Uncontrolled Keywords: MOF; Cd(II); atc; Bioconjugation; Sensing; Anti-bovine serum albumin
Subjects: CSIO > Nano Science and Nano Technology
Divisions: Nano Science and Nano Technology
Depositing User: Ms. Jyotsana
Date Deposited: 17 Feb 2017 11:51
Last Modified: 17 Feb 2017 11:51
URI: http://csioir.csio.res.in/id/eprint/495

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